v1. Metabolic regulation and coordination of the metabolism in bacteria in response to a variety of growth conditions - Efficient biocatalytic systhesis of chiral chemicals - Engineering escherichia coli cell factories for production of organic acids and alcohols - Microbial cell factories for diol production - v2. Principle and performance of gas self-inducing reactors and applications to biotechnology - Novel hydrogen bioreactor and detection apparatus - Reactors for high solid loading preteratment of lignocellulosic biomass - Perturbation experiments: Approaches for metabolic pathway analysis in bioreactor